RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-185
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
SDS-PAGE; Immunofluorescence etc.
Target
NA
Pathway
"MIR-185/AKT,MIR-29a/COLLAGEN signaling pathway"
PubMed ID
Title
MiR-185/AKT and miR-29a/collagen 1a pathways are activated in IPF BAL cells
Year
2016
Function
"MiR-29a and miR-185 were significantly downregulated in IPF BAL cells. Downregulation of miR-29a inversely correlated with the significantly increased levels of COL1A1 mRNA in IPF BAL cells, miR-185 inhibition resulted in significant increase of AKTser473 phosphorylation."